Review

Vol. 57 No. 2 (2022): Turkish Archives of Pediatrics

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Published: Mar 4, 2022
Keywords:
patent ductus arteriosus, preterm, conservative, medical, surgical, treatment

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Ömer Erdeve
Division of Neonatology, Department of Pediatrics, Ankara University, Faculty of Medicine, Ankara, Turkey
Emel Okulu
Division of Neonatology, Department of Pediatrics, Ankara University, Faculty of Medicine, Ankara, Turkey
Yogen Singh
Division of Neonatology, Loma Linda University School of Medicine, California, USA
Richard Sindelar
Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden
Mehmet Yekta Oncel
Division of Neonatology, Buca Seyfi Demirsoy Training and Research Hospital, İzmir, Turkey
Gianluca Terrin
Department of Maternal and Child Health, University of Roma La Sapienza, Rome, Italy
Giovanni Boscarino
Department of Maternal and Child Health, University of Roma La Sapienza, Rome, Italy
Ali Bülbül
Division of Neonatology, Department of Pediatrics University of Health Science, Şişli Hamidiye Etfal Education and Research Hospital, , İstanbul, Turkey
Hannes Sallmon
Department of Congenital Heart Disease/Pediatric Cardiology, Charité–Universitätsmedizin Berlin and Deutsches Herzzentrum Berlin (DHZB), Berlin, Germany
Begüm Atasay
Division of Neonatology, Department of Pediatrics, Ankara University, Faculty of Medicine, Ankara, Turkey
Fahri Ovalı
Division of Neonatology, Department of Pediatrics, İstanbul Medeniyet University, İstanbul, Turkey
Ronald I. Clyman
Department of Pediatrics and Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA, USA

An Update on Patent Ductus Arteriosus and What is Coming Next

Main Article Content

Ömer Erdeve
Division of Neonatology, Department of Pediatrics, Ankara University, Faculty of Medicine, Ankara, Turkey
Emel Okulu
Division of Neonatology, Department of Pediatrics, Ankara University, Faculty of Medicine, Ankara, Turkey
Yogen Singh
Division of Neonatology, Loma Linda University School of Medicine, California, USA
Richard Sindelar
Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden
Mehmet Yekta Oncel
Division of Neonatology, Buca Seyfi Demirsoy Training and Research Hospital, İzmir, Turkey
Gianluca Terrin
Department of Maternal and Child Health, University of Roma La Sapienza, Rome, Italy
Giovanni Boscarino
Department of Maternal and Child Health, University of Roma La Sapienza, Rome, Italy
Ali Bülbül
Division of Neonatology, Department of Pediatrics University of Health Science, Şişli Hamidiye Etfal Education and Research Hospital, , İstanbul, Turkey
Hannes Sallmon
Department of Congenital Heart Disease/Pediatric Cardiology, Charité–Universitätsmedizin Berlin and Deutsches Herzzentrum Berlin (DHZB), Berlin, Germany
Begüm Atasay
Division of Neonatology, Department of Pediatrics, Ankara University, Faculty of Medicine, Ankara, Turkey
Fahri Ovalı
Division of Neonatology, Department of Pediatrics, İstanbul Medeniyet University, İstanbul, Turkey
Ronald I. Clyman
Department of Pediatrics and Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA, USA

Abstract

Patent ductus arteriosus is the most common cardiovascular condition in preterm infants. There is a significant uncertainty about when and how to close ductus arteriosus in preterm infants due to a high spontaneous closure rate even in very immature preterm infants. Diagnosis and management of patent ductus arteriosus remain a challenge for both neonatologists and pediatric cardiologists. Researchers have tried to define a balance between an expectant approach and active treatment in selected infants. This review aimed to focus on the pathophysiology and management of patent ductus arteriosus and to make suggestions about approaches that might eliminate the association of morbidities with patent ductus arteriosus.



Cite this article as: Erdeve Ö, Okulu E, Singh Y, et al. An update on patent ductus arteriosus and what is next?. Turk Arch Pediatr. 2022;57(2):118-131.


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