Prognosis of acute poststreptococcal glomerulonephritis in children

Abstract

<p>The present study was aimed to evaluate the long-term prognosis of acute poststreptococcal glomerulonephritis (APSGN). orty children (10 females, 30 males, mean age at onset 7.8?3 years) with APSGN who were hospitalized in the Pediatric Nephrology Ward between July 1989 and January 2002 were investigated. Twenty three (% 57) patients had a history of upper respiratory tract infection. Physical findings revealed edema in 34 (% 85) patients and hypertension in 12 (% 30) patients. 38 (% 95) patients had macroscopic and/or microscopic hematuria, 4 (% 10) patients protenuria less than 1 g/m2/day, 37 (% 92) patients hypocomplementemia and 8 (% 20) patients uremia. Mean duration of macroscopic hematuria was 8.6 ? 5.3 days. At the last control; GR, serum creatinine level, Na and TRP of the patients were 109 ? 15.1 ml/min/1.73 m2, ortalama 0.77 ? 0.1 mg/dl, 1.28?0.6 % and 89?6 % respectively. None of the patients demonstrated any persistent proteinuria, hematuria and renal function impairment. As a conclusion; our data indicates that the prognosis of APSGN during childhood is good and no permanent renal dysfunction develops.</p>

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<p>?ocuklarda akut poststreptokoksik glomerulonefritin uzun d?nem prognozu</p>

<p>Akut poststreptokoksik glomerulonefritin (APSGN) uzun s?reli prognozunu belirlemek amac?yla Temmuz 1989-Ocak 2002 y?llar? aras?nda ?ocuk Nefroloji servisinde yat?r?larak takip edilen 40 hasta de?erlendirildi. Hastalar?n 10? u (% 25) k?z, 30? u (% 75) erkek olup ya?lar? ortalama 7,8 ? 3 (2-14) y?l idi. Hastalar?n takip s?releri 4,4?2,4 (2-12) y?l aras?nda de?i?mekteydi, % 42,5?u 5 y?ldan daha uzun s?reli takip edilmekteydi. APSGN ?ncesi ?st solunum yolu enfeksiyonu ge?irme ?yk?s? 23 hastada (% 57) mevcuttu. izik muayenede 34 hastada (%85) ?dem, 12 hastada (%30) hipertansiyon bulgular? saptand?. Laboratuvar incelemelerinde 38 hastada (%95) makroskopik ve/veya mikroskopik hemat?ri, 4 hastada (% 10) protein?ri, 37 hastada (% 92) hipokomplementemi, 8 hastada (%20) ?remi saptand?. Protein?ri hi?bir hastada nefrotik d?zeyde (>1gr/m2/g?n) de?ildi. Makroskopik hemat?ri s?resi ortalama 8,6 ? 5,3 g?nd?. Ortalama 4,4?2,4 y?l sonra yap?lan kontrollerinde, glomer?l filtrasyon h?zlar? (GH) ortalama 109 ? 15.3 ml/dak/1.73 m2, serum kreatinin de?erleri ortalama 0,77 ? 0,1 mg/dl, Na: % 1,28?0,6, TRP: % 89?6 olarak saptand?. Hastalar?n hi?birinde mikroskopik hemat?ri, protein?ri, hipertansiyon g?zlenmedi. Sonu? olarak; ?ocukluk ?a??nda APSGN?nin prognozu iyi olup kal?c? b?brek i?lev bozuklu?una yol a?mamaktad?r.</p>